Uridine |58-96-8

Uridine jẹ pyrimidine nucleoside ti o ṣiṣẹ bi ipilẹ ile ipilẹ fun RNA (ribonucleic acid), ọkan ninu awọn oriṣi pataki meji ti awọn acids nucleic pataki fun ibi ipamọ ati gbigbe alaye jiini ninu awọn sẹẹli.

Ilana Kemikali: Uridine ni ipilẹ pyrimidine uracil ti a so mọ ribose suga carbon marun nipasẹ asopọ β-N1-glycosidic.

Ipa ti Ẹmi:

Idina Ilé RNA: Uridine jẹ paati pataki ti RNA, nibiti o ti ṣe ẹhin ẹhin ti awọn ohun elo RNA lẹgbẹẹ awọn nucleosides miiran bii adenosine, guanosine, ati cytidine.

Messenger RNA (mRNA): Ninu mRNA, awọn iṣẹku uridine ṣe koodu alaye jiini lakoko gbigbe, gbigbe awọn ilana lati DNA si ẹrọ iṣelọpọ amuaradagba ninu sẹẹli.

Gbigbe RNA (tRNA): Uridine tun wa awọn ohun elo intRNA, nibiti o ti ṣe alabapin ninu ilana itumọ nipasẹ riri awọn codons kan pato ati jiṣẹ awọn amino acids ti o baamu si ribosome.

Metabolism: Uridine le ṣepọ de novo laarin awọn sẹẹli tabi gba lati awọn orisun ounjẹ.O ti ṣe nipasẹ iyipada enzymatic ti orotidine monophosphate (OMP) tabi uridine monophosphate (UMP) ni ipa ọna biosynthesis pyrimidine.

Pataki nipa ti ara:

Neurotransmitter Precursor: Uridine ṣe ipa kan ninu iṣẹ ọpọlọ ati idagbasoke.O jẹ aṣaaju fun iṣelọpọ ti ọpọlọ phospholipids, pẹlu phosphatidylcholine, eyiti o ṣe pataki fun iduroṣinṣin membran neuronal ati ami ifihan neurotransmitter.

Awọn ipa Neuroprotective: A ti ṣe iwadi Uridine fun awọn ohun-ini neuroprotective ti o pọju ati agbara rẹ lati mu iṣẹ synapti pọ si ati ṣiṣu neuronal.

O pọju iwosan:

Uridine ati awọn itọsẹ rẹ ti ṣe iwadii fun awọn ohun elo itọju ailera ti o pọju ninu awọn rudurudu ti iṣan, pẹlu aisan Alzheimer ati awọn rudurudu iṣesi.

A ti ṣawari afikun Uridine gẹgẹbi imọran lati ṣe atilẹyin iṣẹ iṣaro ati dinku awọn aami aiṣan ti o ni nkan ṣe pẹlu awọn arun neurodegenerative.

Awọn orisun ounjẹ: Uridine jẹ nipa ti ara ni ọpọlọpọ awọn ounjẹ, pẹlu ẹran, ẹja, ẹfọ, ati awọn ọja ifunwara.