Topiroxostat|577778-58-6
Apejuwe ọja:
Topicastat ni ipa idilọwọ ifigagbaga lori xanthine oxidoreductase, nitorinaa idilọwọ iṣelọpọ uric acid.Ko ni ipa idilọwọ lori awọn ensaemusi metabolizing pyrimidine purine miiran, ṣugbọn yiyan ṣe idiwọ ipa Kemikali lori xanthine oxidoreductase.Topicastat ni ipa inhibitory pataki lori mejeeji oxidized ati dinku XOR, nitorinaa ipa rẹ ti idinku uric acid jẹ agbara diẹ sii ati ti o tọ, nitorinaa ọja yii le ṣee lo fun itọju hyperuricemia onibaje ni gout.
