Hyaluronidase |37326-33-3
Ipesi ọja:
Hyaluronidase jẹ enzymu kan ti o le ṣe hydrolyze hyaluronic acid (hyaluronic acid jẹ paati ti matrix tissu ti o ni ipa Itankale ti diwọn omi ati awọn nkan ti o wa ni afikun).
O le dinku iki ti nkan intercellular fun igba diẹ, ṣe igbelaruge idapo subcutaneous, exudate ti o fipamọ ni agbegbe tabi ẹjẹ lati mu iyara kaakiri ati dẹrọ gbigba, ati pe o jẹ kaakiri oogun pataki.
Ti a lo ni ile-iwosan bi oluranlowo permeation oogun lati ṣe agbega gbigba oogun, igbelaruge edema agbegbe tabi itusilẹ hematoma lẹhin iṣẹ abẹ ati ibalokanjẹ.
| Nkan | SPEC |
| Iye owo PH | 5.0 - 8.5 |
| Apakan Iwon | 100% Nipasẹ 80 Mesh |
| Ayẹwo | 98% |
| Isonu lori Gbigbe | ≦5.0% |
| Iṣẹ-ṣiṣe | Ko kere ju 300(400-1000)IU/mg, lori nkan ti o gbẹ |
| Gbigbe ina | T550nm>99.0% |
| Apapọ Awo kika | ≤1000cfu/g |
| Lapapọ iwukara & Mold | ≤100cfu/g |
| Awọn ipo ipamọ | 2-8°C |
Awọn ọja Apejuwe
Apejuwe ọja:
Funfun tabi ina ofeefee flocculent lyophilized nkan na, odorless, awọn iṣọrọ tiotuka ninu omi, insoluble ni ethanol ati acetone, pẹlu ohun ti aipe pH iye ti 4.5-6.0.
Iduroṣinṣin: Ọja ti o gbẹ ni didi ko ni idinku pataki ni pataki lẹhin ti o ti fipamọ ni 4 ℃ fun ọdun kan;
Labẹ ipo ti 42 ℃, iṣẹ naa ko yipada lẹhin alapapo fun awọn iṣẹju 60;Ooru ni 100 ℃ fun iṣẹju 5 lati ṣe idaduro 80% agbara;Awọn solusan olomi ifọkansi kekere jẹ itara si pipaarẹ, ati fifi NaCl le mu iduroṣinṣin wọn pọ si;Rọrun lati bajẹ nigbati o ba farahan si ooru.
Awọn oludena pẹlu awọn ions irin ti o wuwo (Cu2+, HR <2+, Fe <3+ Chemalbook, Mn<2+, Zn<2+), awọn awọ Organic acid, awọn iyọ bile, awọn polyanions, ati awọn polysaccharides iwuwo molikula giga gẹgẹbi Chondroitin sulfate B, heparin, ati heparan sulfate.
Awọn activator ni a polycation.Olusọdipúpọ gbigba ti 1% ojutu olomi ni 280nm jẹ 8. Hyaluronidase ni akọkọ hydrolyzes N-acetyl ni hyaluronic acid- β- Laarin D-glucosamine ati D-glucuronic acid β-1,4-bond, ti n ṣe awọn iṣẹku tetrasaccharide laisi idasilẹ monosaccharides. ifaseyin: hyaluronic acid + H2O oligosaccharides.
Ohun elo:
1. Lo fun iwadi biokemika
2. Ni ile-iwosan, a maa n lo nigbagbogbo lati ṣe igbelaruge ifasilẹ ti edema agbegbe tabi hematoma lẹhin abẹ-abẹ ati ibalokanjẹ, dinku irora ni aaye abẹrẹ, ati ki o mu ki o mu ki abẹrẹ ti abẹ-ara ati awọn abẹrẹ inu iṣan.
3. O tun le ṣee lo fun awọn adhesions oporoku.
Apo: 1g, 5g, 10g, 30g, 50g, 100g, 500g, 1kg, 5 kgs, 10 kgs;25 kgs / apo tabi bi o ba beere.
Ibi ipamọ:Fipamọ si aaye ti o ni afẹfẹ, ibi gbigbẹ.
Standard Alase:International Standard.